Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008678 | 0.87 | TDP1 (0.44) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL5016479 | 0.86 | TTR (0.47) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL17376968 | 0.85 | CA2 (0.46) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL28230178 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| Dipentylamine SCHEMBL6535854 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL21283 | 0.78 | CA2 (0.69) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL30362953 | 0.78 | CA2 (0.69) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL29429225 | 0.78 | CA2 (0.69) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL10344363 | 0.78 | CA2 (0.69) | CYP1A2CYP2C19TDP1HTTHIF1A | |
| SCHEMBL6534971 | 0.78 | CYP1A2 (0.51) | CYP1A2CYP2C19TDP1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | APOSENSE LTD. (IL) | 2006-07-20 | — | — | US | disclosed |
| EP-1643958-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST Neurosurvival Technologies Ltd. (IL) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110339-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | BAD, BAX, CASP3 | CYP1A2 4638/4885CYP2C19 4573/4885TDP1 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.