Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015675 | 0.93 | MAPT (0.59) | MAPTKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL10045813 | 0.85 | MAPT (0.67) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL10045816 | 0.80 | MAPT (0.59) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL5062951 | 0.80 | MAPT (0.49) | MAPTMEN1KMT2AC3AR1ALDH1A1 | |
| SCHEMBL5015698 | 0.79 | FPR2 (0.40) | MAPTKEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL10045817 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL10045814 | 0.78 | MAPT (0.69) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL5054328 | 0.78 | KMT2A (0.46) | MAPTKEAP1NFE2L2KMT2AGHSR | |
| SCHEMBL7735821 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2AC3AR1ALDH1A1 | |
| SCHEMBL10045815 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2AKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |