Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015677 | 0.93 | FPR2 (0.40) | FPR2CTSKMEN1KMT2ALMNA | |
| SCHEMBL5015696 | 0.79 | MAPT (0.56) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL5058970 | 0.76 | KEAP1 (0.38) | CTSKMEN1KMT2ALMNATSHR | |
| SCHEMBL5014193 | 0.72 | CTSK (0.37) | CTSKMAPT | |
| SCHEMBL5015675 | 0.71 | MAPT (0.59) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL5014183 | 0.69 | SLC6A2 (0.46) | CTSKMEN1KMT2ALMNATSHR | |
| SCHEMBL1706602 | 0.69 | FPR2 (0.60) | FPR2MEN1KMT2ALMNATSHR | |
| SCHEMBL7735821 | 0.68 | MAPT (0.47) | CTSKMEN1KMT2ALMNATSHR | |
| SCHEMBL2554277 | 0.68 | HTT (0.49) | MEN1KMT2ALMNATSHRHPGD | |
| SCHEMBL1196722 | 0.67 | ACE (0.45) | CTSKSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |