Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4857912 | 0.99 | OPRD1 (0.35) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| Hydrochloric Acid SCHEMBL4851114 | 0.95 | EHMT2 (0.36) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| SCHEMBL6021758 | 0.93 | OPRD1 (0.36) | OPRD1HTR1AADRA2ADRD2ADRA2C | |
| Hydrochloric Acid SCHEMBL4856230 | 0.93 | OPRD1 (0.35) | OPRD1HTR1AADRA2ADRD2ADRA2C | |
| Hydrochloric Acid SCHEMBL4852104 | 0.91 | OPRD1 (0.34) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| SCHEMBL4260642 | 0.90 | OPRD1 (0.33) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| Hydrochloric Acid SCHEMBL4852449 | 0.89 | OPRD1 (0.34) | OPRD1OPRK1OPRM1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL4859408 | 0.89 | HTR1A (0.35) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| Hydrochloric Acid SCHEMBL4859447 | 0.89 | OPRD1 (0.33) | OPRD1OPRK1OPRM1NTSR1EHMT2 | |
| SCHEMBL6021774 | 0.89 | OPRD1 (0.34) | OPRD1OPRK1OPRM1EHMT2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | claimed |
| US-7410971-B2 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112002-A1 | 1,2-di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH1 | OPRD1 924/4885OPRK1 1360/4885OPRM1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.