Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | EEF2K | O00418 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805199 | 0.85 | EEF2K (0.77) | EEF2KKMT2ATSHRNPSR1KDM4E | |
| SCHEMBL5011383 | 0.81 | ALDH1A1 (0.75) | PDE4BKMT2ATSHRNPSR1KDM4E | |
| SCHEMBL5013141 | 0.80 | ALDH1A1 (0.73) | PDE4BKMT2ATSHRNPSR1KDM4E | |
| SCHEMBL5012380 | 0.79 | KDM4E (0.58) | PDE4BEEF2KKMT2ATSHRNPSR1 | |
| SCHEMBL5012378 | 0.79 | PDE4B (0.93) | PDE4BKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5014730 | 0.79 | PDE4B (0.65) | PDE4BKMT2ANPSR1KDM4EALDH1A1 | |
| SCHEMBL5015874 | 0.79 | PDE4B (0.70) | PDE4BKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4048665 | 0.78 | KDM4E (0.56) | PDE4BEEF2KKMT2AKDM4EALDH1A1 | |
| SCHEMBL4048395 | 0.77 | PDE4B (0.62) | PDE4BEEF2KKMT2AKDM4EALDH1A1 | |
| SCHEMBL5013083 | 0.77 | TSHR (0.71) | PDE4BKMT2ATSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PAGES SANTACANA LUIS MIGUEL | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PDE4A, PDE5A, PDE3B | PDE4B 5/4885EEF2K 3948/4885KMT2A 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.