Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427971 | 0.85 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL5011421 | 0.81 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL5015893 | 0.81 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL4045742 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL5015886 | 0.79 | PDE4B (0.58) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL4046467 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL424777 | 0.78 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL5011413 | 0.78 | HPGD (0.57) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL5014751 | 0.76 | HPGD (0.55) | KDM4EALDH1A1HPGDHIF1ANPSR1 | |
| SCHEMBL4044859 | 0.76 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDHIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PAGES SANTACANA LUIS MIGUEL | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PDE4A, PDE5A, PDE3B | KDM4E 1526/4885ALDH1A1 438/4885HPGD 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.