SCHEMBL5016152

SCHEMBL5016152

Oc1ccccc1C[SiH]1CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.39
MPO P05164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HRH3 Q9Y5N1 1/20 0.37
TSHR P16473 2/20 0.36
CYP2D6 P10635 1/20 0.36
HIF1A Q16665 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
AKR1B1 P15121 1/20 0.35
CA12 O43570 6/20 0.34
CA2 P00918 6/20 0.34
IDO1 P14902 2/20 0.34
CA9 Q16790 5/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KEAP1 Q14145 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22361111 0.80 IDO1 (0.33) IDO1
SCHEMBL16684619 0.80 CYP2A13 (0.39) TSHRTAAR1MAPT
SCHEMBL8837414 0.80 CYP2A13 (0.39) KDM4ETAAR1IDO1MAPT
SCHEMBL8184594 0.78
SCHEMBL16684672 0.76 AR (0.31) KDM4EMAPTHSD17B10
SCHEMBL305088 0.76 ALDH1A1 (0.31)
SCHEMBL11766468 0.76 IDO1 (0.39) KDM4ECYP2D6IDO1
SCHEMBL2727954 0.74 SLC6A4 (0.33) CYP2D6
SCHEMBL3124533 0.74 SLC6A4 (0.45) GAA
SCHEMBL3119376 0.74 CHRNA7 (0.46) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112095172-B High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2023-04-18 CN claimed
CN-112095172-A High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2020-12-18 CN claimed
CN-112095172-B High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2023-04-18 CN disclosed
CN-112095172-A High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2020-12-18 CN disclosed
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed