Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361111 | 0.74 | IDO1 (0.33) | — | |
| SCHEMBL8837414 | 0.74 | CYP2A13 (0.39) | KMT2AKDM4EMAPTHTT | |
| SCHEMBL16684619 | 0.74 | CYP2A13 (0.39) | LMNAKMT2AMAPTHTT | |
| SCHEMBL5016152 | 0.74 | HSPA5 (0.39) | KDM4EMAPT | |
| SCHEMBL8184594 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL7101819 | 0.72 | CALM1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL278240 | 0.72 | CALM1 (0.30) | — | |
| SCHEMBL3124533 | 0.71 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3LMNAKMT2A | |
| SCHEMBL305088 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL11766468 | 0.71 | IDO1 (0.39) | SLC6A4SLC6A2POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1927636-B1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20080160323-A1 | Hydrosilation catalysts; for encapsulating semiconductors | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2008-07-03 | — | — | US | disclosed |
| EP-1927636-A1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | Rohm and Haas Company (US) | 2008-06-04 | — | — | EP | disclosed |