Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355746 | 0.76 | TSHR (0.46) | TSHRCALM1TDP1IDO1THRB | |
| SCHEMBL3482200 | 0.73 | TSHR (0.43) | TSHRCALM1TDP1IDO1THRB | |
| SCHEMBL7101824 | 0.73 | IDO1 (0.39) | TSHRCALM1IDO1LOXL2AGXT | |
| SCHEMBL2510929 | 0.73 | TP53 (0.39) | TSHRCALM1TDP1IDO1ALDH1A1 | |
| SCHEMBL819896 | 0.72 | TSHR (0.48) | TSHRCALM1TDP1IDO1THRB | |
| SCHEMBL3237076 | 0.72 | TSHR (0.48) | TSHRCALM1TDP1IDO1THRB | |
| SCHEMBL30447961 | 0.71 | TSHR (0.36) | TSHRCALM1TDP1IDO1ALDH1A1 | |
| SCHEMBL28455843 | 0.70 | TSHR (0.38) | TSHRALDH1A1TP53LMNA | |
| SCHEMBL28455844 | 0.69 | TSHR (0.36) | TSHRTRPA1SLC6A2SLC6A3 | |
| SCHEMBL15302282 | 0.69 | TSHR (0.43) | TSHRCALM1TDP1IDO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393911-B2 | Organosilicon fine particles and method of producing same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20060089478-A1 | antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2006-04-27 | — | — | US | disclosed |