Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016505 | 0.86 | MAPK9 (0.37) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL3545762 | 0.80 | THRA (0.41) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL3545422 | 0.79 | CA2 (0.41) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL11928842 | 0.76 | CA2 (0.37) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL3540537 | 0.76 | KMT2A (0.47) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL3547492 | 0.75 | MEN1 (0.54) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL3545420 | 0.74 | MEN1 (0.50) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL13998433 | 0.74 | MAPK9 (0.48) | MAPK9MAPK10CA2MEN1KMT2A | |
| SCHEMBL924672 | 0.73 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2ACXCR3 | |
| SCHEMBL2419998 | 0.72 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409483-B1 | ARYLSULFONAMIDE DERIVATIVES AS C-JUN-N-TERMINAL KINASES (JNK'S) INHIBITORS | SERONO LAB (CH) | 2008-12-31 | — | — | EP | claimed |