Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.80 |
| ▸ | CNR2 | P34972 | 10/20 | 0.65 |
| ▸ | CNR1 | P21554 | 7/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016654 | 1.00 | MAPT (0.80) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL16619553 | 0.92 | MAPT (0.83) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL16619551 | 0.92 | MAPT (0.83) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4982184 | 0.89 | MEN1 (1.00) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6517985 | 0.89 | MEN1 (1.00) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4982180 | 0.89 | MEN1 (1.00) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14671455 | 0.86 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14671339 | 0.86 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14671461 | 0.86 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5015349 | 0.84 | CNR2 (0.71) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036383-A3 | USE OF A PROTEIN TYROSINE KINASE INHIBITOR FOR INDUCING THE DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARDIOGENIC CELLS | 파미셀 주식회사 (KR) | 2012-05-10 | — | — | WO | disclosed |
| EP-1927587-B1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-1927587-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC.WW | 2005-04-07 | — | — | US | disclosed |
| EP-1520850-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | TAS2R41, TAS2R42, TAS2R14 | MAPT 3925/4885KMT2A 1321/4885MEN1 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.