Valeric Acid

Valeric Acid

SCHEMBL50167

CC(=O)O.CCCCC(=O)O

nearest known ligand 0.74

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Valeric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.70
AKR1B1 P15121 1/20 0.74
GPR84 Q9NQS5 7/20 0.70
PPARG P37231 7/20 0.70
PPARD Q03181 7/20 0.70
PPARA Q07869 7/20 0.70
HDAC11 Q96DB2 5/20 0.70
TSHR P16473 4/20 0.70
PTPN1 P18031 3/20 0.70
ALDH1A1 P00352 2/20 0.70
TLR2 O60603 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
FABP4 P15090 2/20 0.70
KMT2A Q03164 2/20 0.70
SLC22A6 Q4U2R8 2/20 0.70
SLC22A8 Q8TCC7 1/20 0.70
MEN1 O00255 1/20 0.70
ALOX15 P16050 1/20 0.70
PDE4A P27815 1/20 0.70
PDE3A Q14432 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valeric Acid SCHEMBL386697 1.00 AKR1B1 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL28060341 1.00 AKR1B1 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL566579 0.95 AKR1B1 (0.67) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL1237974 0.95 FFAR3 (0.68) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL2553774 0.94 AKR1B1 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL30381737 0.94
Valeric Acid SCHEMBL30442925 0.94
Valeric Acid SCHEMBL1331662 0.94
Valeric Acid SCHEMBL5886 0.94
Valeric Acid SCHEMBL1333240 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058279-B Curved screen protective film, preparation method and application thereof 安徽屹珹新材料科技有限公司 2023-12-08 CN claimed
US-11723873-B2 Oral dosage form of ticagrelor and preparation method thereof Elite Pharmaceutical Solution Inc. (US) 2023-08-15 US claimed
CN-115715184-A Ticagrelor oral dosage form and preparation method thereof 赛乐医药科技有限公司 2023-02-24 CN claimed
WO-2022271167-A1 ORAL DOSAGE FORM OF TICAGRELOR AND PREPARATION METHOD THEREOF Elite Pharmaceutical Solution Inc. (US) 2022-12-29 WO claimed
US-20220409545-A1 ORAL DOSAGE FORM OF TICAGRELOR AND PREPARATION METHOD THEREOF Elite Pharmaceutical Solution Inc. (US) 2022-12-29 US claimed
CN-114058279-A Curved screen protective film, preparation method and application thereof 安徽屹珹新材料科技有限公司 2022-02-18 CN claimed
CN-107936186-B 3D printing wire and preparation method thereof 中国石油化工股份有限公司 2020-06-09 CN claimed
EP-1335045-B1 THERMOPLASTIC CELLULOSE DERIVATIVE COMPOSITION AND FIBER COMPRISING THE SAME TORAY INDUSTRIES (JP) 2016-12-28 EP claimed
WO-2013168177-A2 OSMOTICALLY CONTROLLED DRUG DELIVERY SYSTEMS RUBICON RESEARCH PRIVATE LIMITED (IN) 2013-11-14 WO claimed
US-8529955-B2 Methods of treatment using a gastric retained gabapentin dosage DEPOMED, INC. (US) 2013-09-10 US claimed
EP-0626986-B1 AQUEOUS DISPERSION USEFUL IN COATINGS CONTAINING HYDROLYZED CELLULOSE ESTER AND ACRYLIC RESIN EASTMAN CHEM CO (US) 1996-03-20 EP claimed
EP-0626986-A1 AQUEOUS DISPERSION USEFUL IN COATINGS CONTAINING HYDROLYZED CELLULOSE ESTER AND ACRYLIC RESIN. EASTMAN CHEM CO (US) 1994-12-07 EP claimed
US-5334638-A Aqueous dispersion useful in coatings containing hydrolyzed cellulose ester and acyrlic resin EASTMAN CHEMICAL COMPANY (US) 1994-08-02 US claimed
WO-1993014168-A1 AQUEOUS DISPERSION USEFUL IN COATINGS CONTAINING HYDROLYZED CELLULOSE ESTER AND ACRYLIC RESIN EASTMAN KODAK COMPANY (US) 1993-07-22 WO claimed
EP-0227093-B1 CELLULOSIC BINDER FOR DYE-DONOR ELEMENT USED IN THERMAL DYE TRANSFER EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-11-07 EP claimed
US-4700207-A CELLULOSE TRIACETATE OR CELLULOSE MIXED ESTER EASTMAN KODAK COMPANY (US) 1987-10-13 US claimed
EP-0227093-A2 Cellulosic binder for dye-donor element used in thermal dye transfer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-07-01 EP claimed
US-4111203-A OSMOTIC SYSTEM WITH MEANS FOR IMPROVING DELIVERY KINETICS OF SYSTEM ALZA CORPORATION (US) 1978-09-05 US claimed
US-4111202-A OSMOTIC SYSTEM FOR THE CONTROLLED AND DELIVERY OF AGENT OVER TIME ALZA CORPORATION (US) 1978-09-05 US claimed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723873-B2 Oral dosage form of ticagrelor and preparation method thereof TMEM165, ABCB11, ABCG2 ESR1 1758/4885AKR1B1 2759/4885GPR84 956/4885
US-20220409545-A1 ORAL DOSAGE FORM OF TICAGRELOR AND PREPARATION METHOD THEREOF TMEM165, ABCB11, ABCG2 ESR1 1758/4885AKR1B1 2759/4885GPR84 956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.