Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | BLM | P54132 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP2 | O95551 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016886 | 1.00 | DNM1 (0.61) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15020041 | 0.89 | DNM1 (0.69) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15020045 | 0.89 | DNM1 (0.69) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15039495 | 0.89 | DNM1 (0.69) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15022708 | 0.84 | DNM1 (0.62) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15022710 | 0.84 | DNM1 (0.62) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15039490 | 0.84 | DNM1 (0.61) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15039538 | 0.84 | DNM1 (0.61) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15020365 | 0.84 | DNM1 (0.61) | DNM1RAB9ABLMMAPTMAPK1 | |
| SCHEMBL15020366 | 0.84 | DNM1 (0.61) | DNM1RAB9ABLMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115468994-A | Porous nanogold sensor | 嘉兴学院 | 2022-12-13 | — | — | CN | disclosed |
| US-7449584-B2 | N-(2((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide Crystalline Form 1 | ABBOTT LABORATORIES INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-7446206-B2 | N-((2Z)-2-((4-hydroxyphenyl) amino)-1,2-dihydro-3-pyridinyl)-4-methoxybenzenesulfonamide crystalline form 2 | ABBOTT LABORATORIES INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070099967-A1 | causing nucleation in mixture with solvent between about 60 degrees C. and 100 degrees C., supersaturated; and isolating Crystalline Form 1 | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070021470-A1 | Crystalline N-(2-((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide methanolates | ABBOTTLABORATORIES | 2007-01-25 | — | — | US | disclosed |
| US-20070021471-A1 | Crystalline N-(2-((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide ethanolates | ABBOTT LABORATORIES | 2007-01-25 | — | — | US | disclosed |
| US-20070004782-A1 | N-((2Z)-2-((4-Hydroxyphenyl) amino)-1,2-dihydro-3-pyridinyl)-4-methoxybenzenesulfonamide Crystalline Form 2 | ABBVIE INC. | 2007-01-04 | — | — | US | disclosed |
| US-20060293367-A1 | Amorphous N-(2-((4-hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide | ABBOTT LABORATORIES | 2006-12-28 | — | — | US | disclosed |
| US-20060293368-A1 | Amorphous N-(2-((4-hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide hydrochloride | ABBOTT LABORATORIES | 2006-12-28 | — | — | US | disclosed |