Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 10/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024539 | 0.88 | SLC6A5 (0.62) | SLC6A5TP53THRBMEN1KMT2A | |
| SCHEMBL5017582 | 0.87 | SLC6A5 (0.77) | SLC6A5TP53CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5016040 | 0.76 | SLC6A5 (0.83) | SLC6A5TP53HTR2A | |
| SCHEMBL6711114 | 0.76 | TP53 (0.59) | SLC6A5TP53THRBMEN1KMT2A | |
| SCHEMBL5015906 | 0.75 | SLC6A5 (0.81) | SLC6A5TP53HTR2A | |
| SCHEMBL5017542 | 0.75 | SLC6A5 (1.00) | SLC6A5TP53MEN1KMT2AHTR2A | |
| SCHEMBL5022643 | 0.74 | SLC6A5 (1.00) | SLC6A5TP53THRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL26654518 | 0.74 | SLC6A5 (1.00) | SLC6A5TP53MEN1KMT2AHTR2A | |
| SCHEMBL6013403 | 0.70 | SLC6A5 (0.89) | SLC6A5TP53THRBMEN1KMT2A | |
| SCHEMBL16233251 | 0.69 | SLC6A5 (0.83) | SLC6A5TP53MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419138-B1 | N- (1-DIMETHYLAMINOCYCLOALKYL)METHYL BENZAMIDE DERIVATIVES | ORGANON NV (NL) | 2008-10-29 | — | — | EP | disclosed |