Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 11/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016040 | 0.88 | SLC6A5 (0.83) | SLC6A5TP53HTR2AP2RX3OPRM1 | |
| SCHEMBL5015906 | 0.87 | SLC6A5 (0.81) | SLC6A5TP53HTR2AP2RX3OPRM1 | |
| SCHEMBL5017583 | 0.87 | SLC6A5 (0.59) | SLC6A5TP53HTR2ACHRNB2CHRNB4 | |
| SCHEMBL5017542 | 0.87 | SLC6A5 (1.00) | SLC6A5TP53HTR2AP2RX3L3MBTL1 | |
| SCHEMBL5022643 | 0.86 | SLC6A5 (1.00) | SLC6A5TP53HTR2AP2RX3OPRM1 | |
| Hydrochloric Acid SCHEMBL26654518 | 0.86 | SLC6A5 (1.00) | SLC6A5TP53HTR2AP2RX3L3MBTL1 | |
| SCHEMBL6013403 | 0.82 | SLC6A5 (0.89) | SLC6A5TP53HTR2AP2RX3L3MBTL1 | |
| SCHEMBL16233251 | 0.81 | SLC6A5 (0.83) | SLC6A5TP53HTR2AP2RX3L3MBTL1 | |
| SCHEMBL16233255 | 0.79 | SLC6A5 (0.80) | SLC6A5TP53HTR2AP2RX3L3MBTL1 | |
| SCHEMBL5017789 | 0.79 | TP53 (1.00) | SLC6A5TP53HTR2AP2RX3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419138-B1 | N- (1-DIMETHYLAMINOCYCLOALKYL)METHYL BENZAMIDE DERIVATIVES | ORGANON NV (NL) | 2008-10-29 | — | — | EP | disclosed |
| US-7126027-B2 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | AKZO NOBEL N.V. (NL) | 2006-10-24 | — | — | US | disclosed |
| US-20040242685-A1 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | N.V. ORGANON (NL) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242685-A1 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | SLC1A2, SLC6A1, KCNT2 | SLC6A5 26/4885TP53 4820/4885HTR2A 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.