⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL20595533 | 1.00 | — | — | |
| Thiophene SCHEMBL29642517 | 1.00 | — | — | |
| Thiophene SCHEMBL1539835 | 0.81 | — | — | |
| Thiophene SCHEMBL9620475 | 0.79 | — | — | |
| Glyoxylate SCHEMBL4152113 | 0.78 | ALDH1A1 (0.35) | — | |
| Thiophene SCHEMBL31622302 | 0.76 | — | — | |
| Thiophene SCHEMBL28521205 | 0.76 | — | — | |
| Thiophene SCHEMBL3008745 | 0.76 | — | — | |
| Thiophene SCHEMBL6493449 | 0.76 | TSHR (0.40) | — | |
| Thiophene SCHEMBL225198 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804037-B | Thiophene formic acid beta-caryophyllene-5-ester compound and preparation method and application thereof | 南京林业大学 | 2022-05-17 | — | — | CN | claimed |
| CN-113214236-B | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-113214236-A | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2021-08-06 | — | — | CN | claimed |
| CN-110105622-B | High-performance composite heat stabilizer | 广州湘环新材料有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112279869-A | Novel production process of ceftiofur | 菏泽宇隆生物科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-110804037-A | Thiophene formic acid β -caryophyllene-5-ester compound and preparation method and application thereof | 南京林业大学 | 2020-02-18 | — | — | CN | claimed |
| CN-109251192-A | 3 or 4 position trifluoromethyls replace the preparation method of isocoumarin | 江西师范大学 | 2019-01-22 | — | — | CN | claimed |
| CN-106866646-A | It is a kind of to be used to synthesize the new catalytic direct dehydrogenation coupling method containing thiophene-structure alkane compound | 湖南大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106187993-A | A kind of micro passage reaction synthesizes the method for 5 chlorine 2 formyl chloride thiophene | 黑龙江鑫创生物科技开发有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-118496197-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115058743-A | Novel composite electrolyte and method for low-temperature electrolytic refining of secondary aluminum by using same | 昆明理工大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-110804037-B | Thiophene formic acid beta-caryophyllene-5-ester compound and preparation method and application thereof | 南京林业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110804037-B | Thiophene formic acid beta-caryophyllene-5-ester compound and preparation method and application thereof | 南京林业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110804037-B | Thiophene formic acid beta-caryophyllene-5-ester compound and preparation method and application thereof | 南京林业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-103570672-B | Benzoyl hydrazine compound containing thiophene ring, and preparation method and application of compound | UNIV SOUTH CHINA AGRICULT | 2015-06-17 | — | — | CN | disclosed |
| CN-103570672-A | Benzoyl hydrazine compound containing thiophene ring, and preparation method and application of compound | UNIV SOUTH CHINA AGRICULT | 2014-02-12 | — | — | CN | disclosed |
| CN-101519410-A | Preparation method for metallic thiophene ring ternary complex with anti-cancer activity and application thereof | UNIV SHANGHAI | 2009-09-02 | — | — | CN | disclosed |
| EP-1311475-B1 | AMINOCYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |
| CN-101139337-A | Novel method for preparing substituted thenoic acid ester and uses thereof | BEIJING XINLINGXIAN MEDICAL TE (CN) | 2008-03-12 | — | — | CN | disclosed |
| CN-1119867-A | Cephalosporin derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1996-04-03 | — | — | CN | disclosed |