Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyoxylate SCHEMBL1443846 | 0.97 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1HCAR2 | |
| Glyoxylate SCHEMBL27691861 | 0.97 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1HCAR2 | |
| Glyoxylate SCHEMBL28504188 | 0.97 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1HCAR2 | |
| Maleic Acid SCHEMBL27485086 | 0.82 | TSHR (0.53) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Fumaric Acid SCHEMBL10620517 | 0.82 | TSHR (0.53) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Maleic Acid SCHEMBL10620502 | 0.82 | TSHR (0.53) | ALDH1A1HCAR2TSHRTP53EGLN1 | |
| Thiophene SCHEMBL1616682 | 0.81 | — | — | |
| Thiophene SCHEMBL20482064 | 0.81 | CA1 (0.39) | — | |
| Benzene SCHEMBL4653866 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1HCAR2TSHR | |
| Thiophene SCHEMBL7050121 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245688-B | Conductive composite material and thermoelectric device comprising same | 3M INNOVATIVE PROPERTIES CO | 2014-03-12 | — | — | CN | claimed |
| CN-101880271-B | Synthesis method of 2-thiophene acetylchloride | Lianyungang hongye chemical industry co ltd | 2012-11-28 | — | — | CN | claimed |
| CN-102245688-A | Conductive composite material and thermoelectric device comprising same | 3M INNOVATIVE PROPERTIES CO | 2011-11-16 | — | — | CN | claimed |
| CN-101880271-A | Synthesis method of 2-thiophene acetylchloride | Lianyungang hongye chemical industry co ltd | 2010-11-10 | — | — | CN | claimed |
| US-20090209465-A1 | MCT1 Transporters Expressed in Blood Brain Barrier Cells | XENOPORT, INC. (US) | 2009-08-20 | — | — | US | claimed |
| US-7452680-B2 | Using monocarboxylate transporter 1 (MCT1) as diagnostic tool in detecting modulators for prevention and treatment of nervous system disorders | XENOPORT, INC. (US) | 2008-11-18 | — | — | US | claimed |
| WO-2005075992-A1 | MCT1 TRANSPORTER EXPRESSED IN BLOOD BRAIN BARRIER CELLS | XENOPORT, INC. (US) | 2005-08-18 | — | — | WO | claimed |
| US-20050170390-A1 | MCT1 transporters expressed in blood brain barrier cells | XENOPORT, INC. (US) | 2005-08-04 | — | — | US | claimed |
| US-20240208895-A1 | BRANCHED-CHAIN AMINO ACID DERIVATIVES TO TREAT DISEASE | Intrabio Ltd. (GB) | 2024-06-27 | — | — | US | disclosed |
| CN-118184625-A | Synthesis method of 2-thiopheneacetic acid | 浙江东盈药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2022264037-A1 | BRANCHED-CHAIN AMINO ACID DERIVATIVES TO TREAT DISEASE | Intrabio Ltd. (GB) | 2022-12-22 | — | — | WO | disclosed |
| CN-113552782-A | Light-responsive material, adhesive, photoswitch material, toner, and image forming method | 柯尼卡美能达株式会社 | 2021-10-26 | — | — | CN | disclosed |
| CN-103992302-A | Synthesis process of 2-thiopheneacetic acid | SHANGQIU KOREATA CHEMICAL CO LTD | 2014-08-20 | — | — | CN | disclosed |
| CN-102977073-B | Method for synthesizing 2-thiophene acetic acid through 2-thiophene alcohol | UNIV SHANDONG NORMAL | 2014-05-14 | — | — | CN | disclosed |
| WO-2005098444-A2 | MONOCARBOXYLATE TRANSPORTERS EXPRESSED IN CANCER CELLS | XENOPORT, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005075992-A1 | MCT1 TRANSPORTER EXPRESSED IN BLOOD BRAIN BARRIER CELLS | XENOPORT, INC. (US) | 2005-08-18 | — | — | WO | disclosed |
| US-20050170390-A1 | MCT1 transporters expressed in blood brain barrier cells | XENOPORT, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050032135-A1 | Monocarboxylate transporters expressed in cancer cells | XENOPORT, INC. (US) | 2005-02-10 | — | — | US | disclosed |
| CN-1382140-A | Neurotrophic pyrrolidines and piperidines and related compositions containing them | ORTHO MCNEIL PHARM INC (US) | 2002-11-27 | — | — | CN | disclosed |
| US-4369206-A | HARDENING COATING WITH AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032135-A1 | Monocarboxylate transporters expressed in cancer cells | SLC16A1, SLC16A3, SLC16A8 | ALDH1A1 523/4885MAPK1 3089/4885TDP1 3152/4885 |
| US-20240208895-A1 | BRANCHED-CHAIN AMINO ACID DERIVATIVES TO TREAT DISEASE | CTSA, GBA1, GAA | ALDH1A1 2303/4885MAPK1 3010/4885TDP1 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.