Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 15/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.50 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.50 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924273 | 0.85 | KCNH3 (1.00) | KCNH3ROCK1RECQLMCL1 | |
| SCHEMBL13421020 | 0.82 | KCNH3 (0.69) | KCNH3RECQLMCL1FCGR3BFCGR1A | |
| SCHEMBL13420924 | 0.82 | KCNH3 (0.69) | KCNH3RECQLMCL1FCGR3BFCGR1A | |
| SCHEMBL2569220 | 0.81 | L3MBTL1 (0.70) | KCNH3 | |
| SCHEMBL13421016 | 0.80 | KCNH3 (0.66) | KCNH3RECQLMCL1FCGR3BFCGR1A | |
| SCHEMBL1923769 | 0.79 | KCNH3 (0.67) | KCNH3RECQLMCL1 | |
| SCHEMBL4544863 | 0.79 | KCNH3 (0.70) | KCNH3RECQLMCL1 | |
| SCHEMBL22151175 | 0.79 | APP (0.64) | KCNH3 | |
| SCHEMBL13421047 | 0.79 | KCNH3 (0.64) | KCNH3RECQLMCL1FCGR3BFCGR1A | |
| SCHEMBL19598922 | 0.77 | KCNH3 (0.63) | KCNH3RECQLMCL1FCGR3BFCGR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |