Zimidoben

Zimidoben

SCHEMBL501789

O=C(OCCn1ccnc1)c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 13/20 0.60
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
CYP19A1 P11511 1/20 0.52
TDP1 Q9NUW8 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL501417 0.92 CYP19A1 (0.57) TBXAS1MEN1LMNAKMT2ACYP19A1
SCHEMBL25320881 0.85 CYP19A1 (0.55) TBXAS1CYP19A1
SCHEMBL502074 0.84 HRH3 (0.56) TBXAS1MEN1LMNAKMT2ACYP19A1
SCHEMBL502376 0.83 TBXAS1 (0.65) TBXAS1MEN1LMNAKMT2ACYP19A1
SCHEMBL10655959 0.82 TBXAS1 (0.61) TBXAS1MEN1LMNAKMT2ATDP1
SCHEMBL14369841 0.81 TDP1 (0.61) LMNAKMT2ATDP1SMN1; SMN2ALDH1A1
SCHEMBL10651131 0.79 CYP19A1 (0.55) TBXAS1MEN1LMNAKMT2ACYP19A1
SCHEMBL10739517 0.79 GLA (0.53) TBXAS1MEN1LMNAKMT2AALDH1A1
SCHEMBL501977 0.79 TBXAS1 (0.58) TBXAS1LMNATDP1ALDH1A1
SCHEMBL31518372 0.79 TBXAS1 (0.58) TBXAS1LMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-0124186-B1 IMIDAZOLE-ETHANOL ESTERS GIST-BROCADES N.V. (NL) 1988-09-21 EP claimed
US-4710571-A LIPID INHIBITORS GIST-BROCADES N.V. (NL) 1987-12-01 US claimed
US-4563473-A TREATMENT OF ACNE AND SEBORRHEA GIST-BROCADES N.V. (NL) 1986-01-07 US claimed
EP-0124186-A2 Imidazole-ethanol esters GIST-BROCADES N.V. (NL) 1984-11-07 EP claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
EP-2033966-B1 Novel photoacid generators, resist compositons, and patterning processes SHINETSU CHEMICAL CO (JP) 2015-07-29 EP disclosed
US-8945809-B2 Fluorinated monomer, fluorinated polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-02-03 US disclosed
US-8933251-B2 Fluorinated monomer of cyclic acetal structure, polymer, resist protective coating composition, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-13 US disclosed
US-8609889-B2 Photoacid generator, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-12-17 US disclosed
US-20130231491-A1 FLUORINATED MONOMER OF CYCLIC ACETAL STRUCTURE, POLYMER, RESIST PROTECTIVE COATING COMPOSITION, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-09-05 US disclosed
US-8454582-B2 Methods and devices for the treatment of ocular conditions SURMODICS, INC. (US) 2013-06-04 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
US-5744488-A 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS PFIZER INC. (US) 1998-04-28 US disclosed
EP-0124186-B1 IMIDAZOLE-ETHANOL ESTERS GIST-BROCADES N.V. (NL) 1988-09-21 EP disclosed
US-4710571-A LIPID INHIBITORS GIST-BROCADES N.V. (NL) 1987-12-01 US disclosed
US-4563473-A TREATMENT OF ACNE AND SEBORRHEA GIST-BROCADES N.V. (NL) 1986-01-07 US disclosed
EP-0124186-A2 Imidazole-ethanol esters GIST-BROCADES N.V. (NL) 1984-11-07 EP disclosed