Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708370 | 0.85 | ALDH1A1 (0.59) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL8299354 | 0.85 | ALDH1A1 (0.59) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL4322573 | 0.85 | ALDH1A1 (0.47) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL4328109 | 0.85 | ALDH1A1 (0.47) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL4322569 | 0.85 | ALDH1A1 (0.47) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL14770231 | 0.82 | ELANE (0.50) | CYP2D6ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL25097911 | 0.81 | NR1H2 (0.47) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL4320166 | 0.81 | NR1H2 (0.47) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL20494301 | 0.81 | CYP3A4 (0.45) | CYP2D6ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL20494302 | 0.81 | CYP3A4 (0.45) | CYP2D6ALDH1A1KMT2AMMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | CYP2D6 2747/4885ALDH1A1 4062/4885KMT2A 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.