Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 11/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019757 | 0.94 | IL2 (0.42) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL5019755 | 0.88 | IL2 (0.40) | IL2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10101255 | 0.83 | IL2 (0.44) | IL2STIM1ORAI1ORAI2NPC1 | |
| Hydrochloric Acid SCHEMBL614866 | 0.82 | IL2 (0.44) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL7928314 | 0.82 | IL2 (0.49) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL7922608 | 0.81 | IL2 (0.43) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL5019743 | 0.81 | PTPN11 (0.33) | IL2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL614560 | 0.81 | IL2 (0.43) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL1782159 | 0.80 | IL2 (0.42) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL1783793 | 0.80 | IL2 (0.42) | IL2STIM1ORAI1ORAI2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |