Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019753 | 0.88 | IL2 (0.39) | KDM4EKMT2ARAB9ASMN1; SMN2MAP3K5 | |
| SCHEMBL5019608 | 0.88 | TP53 (0.39) | CRACR2AKDM4EKMT2ATP53RAB9A | |
| SCHEMBL3825366 | 0.81 | IL2 (0.44) | KDM4EKMT2ARAB9AMAP3K5 | |
| SCHEMBL17375135 | 0.80 | GRM5 (0.38) | KDM4EKMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL5019603 | 0.79 | KMT2A (0.39) | KDM4EKMT2ATP53RAB9ASMN1; SMN2 | |
| SCHEMBL5019579 | 0.79 | KMT2A (0.39) | KDM4EKMT2ATP53RAB9ASMN1; SMN2 | |
| SCHEMBL3826508 | 0.79 | KMT2A (0.47) | KDM4EKMT2ATP53RAB9ASMN1; SMN2 | |
| SCHEMBL8186422 | 0.78 | IL2 (0.40) | KDM4EKMT2ARAB9AMAP3K5 | |
| SCHEMBL12650398 | 0.78 | IL2 (0.40) | KDM4EKMT2ARAB9AMAP3K5 | |
| SCHEMBL3824488 | 0.78 | IL2 (0.42) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |