Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019741 | 0.88 | CRACR2A (0.38) | SMN1; SMN2KMT2AMAP3K5RAB9AMAPT | |
| SCHEMBL3825366 | 0.84 | IL2 (0.44) | IL2NPC1KMT2AMAP3K5RAB9A | |
| SCHEMBL17375135 | 0.83 | GRM5 (0.38) | SMN1; SMN2NPC1KMT2ARAB9ANPY5R | |
| SCHEMBL3824488 | 0.83 | IL2 (0.42) | IL2KMT2AALDH1A1MAPTHTR1F | |
| SCHEMBL5019579 | 0.82 | KMT2A (0.39) | IL2SMN1; SMN2NPC1KMT2AMAP3K5 | |
| SCHEMBL5019603 | 0.82 | KMT2A (0.39) | IL2SMN1; SMN2NPC1KMT2AMAP3K5 | |
| SCHEMBL5019608 | 0.82 | TP53 (0.39) | SMN1; SMN2NPC1KMT2AALDH1A1RAB9A | |
| SCHEMBL3826508 | 0.82 | KMT2A (0.47) | SMN1; SMN2NPC1KMT2AMAP3K5ALDH1A1 | |
| SCHEMBL8186422 | 0.82 | IL2 (0.40) | IL2NPC1KMT2AMAP3K5RAB9A | |
| SCHEMBL12650398 | 0.81 | IL2 (0.40) | IL2NPC1KMT2AMAP3K5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |