Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 3/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019579 | 0.89 | KMT2A (0.39) | MAP3K5KMT2AIL2WNT1GSK3B | |
| SCHEMBL3826508 | 0.87 | KMT2A (0.47) | MAP3K5ABL1KMT2AWNT1GSK3B | |
| SCHEMBL3827961 | 0.86 | HTR1F (0.42) | MAP3K5KMT2AIL2WNT1GSK3B | |
| SCHEMBL10819910 | 0.86 | MAP3K5 (0.39) | MAP3K5KMT2AIL2WNT1GSK3B | |
| SCHEMBL5019603 | 0.86 | KMT2A (0.39) | MAP3K5KMT2AIL2WNT1GSK3B | |
| SCHEMBL5019627 | 0.86 | CSNK1D (0.37) | MAP3K5ABL1IL2WNT1GSK3B | |
| SCHEMBL3825366 | 0.85 | IL2 (0.44) | MAP3K5KMT2AIL2 | |
| SCHEMBL5019588 | 0.84 | GRM5 (0.36) | MAP3K5IL2WNT1GSK3BDYRK1A | |
| SCHEMBL4561040 | 0.83 | KMT2A (0.35) | KMT2AIL2 | |
| SCHEMBL4999489 | 0.83 | HDAC4 (0.35) | WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |