Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283710 | 0.86 | BTN3A1 (0.57) | LMNABTN3A1TSHRLTA4H | |
| SCHEMBL13622273 | 0.86 | BTN3A1 (0.44) | BTN3A1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL18597500 | 0.82 | BTN3A1 (0.54) | LMNABTN3A1POLBMEN1KMT2A | |
| SCHEMBL19187048 | 0.81 | BTN3A1 (0.50) | BTN3A1TDP1 | |
| SCHEMBL19187124 | 0.80 | LMNA (0.44) | LMNABTN3A1MEN1KMT2A | |
| SCHEMBL21581139 | 0.80 | BTN3A1 (0.40) | LMNABTN3A1TSHRTDP1L3MBTL1 | |
| SCHEMBL15765579 | 0.78 | BTN3A1 (0.46) | LMNABTN3A1TSHRTDP1L3MBTL1 | |
| SCHEMBL13652726 | 0.78 | BTN3A1 (0.46) | LMNABTN3A1TSHRTDP1L3MBTL1 | |
| SCHEMBL18583838 | 0.77 | BTN3A1 (0.58) | LMNABTN3A1TSHR | |
| SCHEMBL20059011 | 0.77 | BTN3A1 (0.38) | BTN3A1POLBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2696679-B1 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2012062870-A1 | URACYL SPIROOXETANE NUCLEOSIDE PHOSPHORAMIDATES | JANSSEN PRODUCTS, LP (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062869-A1 | URACYL SPIROOXETANE NUCLEOSIDE PHOSPHORAMIDATES | JANSSEN PRODUCTS, LP (US) | 2012-05-18 | — | — | WO | disclosed |