Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875648 | 0.87 | BTN3A1 (0.56) | BTN3A1TSHRLTA4H | |
| SCHEMBL5019769 | 0.86 | LMNA (0.46) | BTN3A1POLBTSHRTDP1L3MBTL1 | |
| SCHEMBL14044811 | 0.82 | BTN3A1 (0.53) | BTN3A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL1273568 | 0.81 | BTN3A1 (0.49) | BTN3A1TDP1 | |
| SCHEMBL13875657 | 0.80 | ALDH1A1 (0.47) | L3MBTL1MEN1KMT2A | |
| SCHEMBL21581139 | 0.79 | BTN3A1 (0.40) | BTN3A1POLBHDAC3TSHRTDP1 | |
| SCHEMBL21158536 | 0.79 | BTN3A1 (0.45) | BTN3A1HDAC3TSHRTDP1L3MBTL1 | |
| SCHEMBL12467473 | 0.79 | BTN3A1 (0.45) | BTN3A1HDAC3TSHRTDP1L3MBTL1 | |
| SCHEMBL19650266 | 0.77 | BTN3A1 (0.57) | BTN3A1TSHRMEN1KMT2A | |
| SCHEMBL28445426 | 0.77 | SRC (0.46) | BTN3A1TDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142827-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTION | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-11-26 | — | — | WO | disclosed |