Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542705 | 0.85 | TSHR (0.63) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL12203843 | 0.82 | TSHR (0.68) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL4537993 | 0.81 | TSHR (0.59) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL4537992 | 0.81 | TSHR (0.59) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL12657603 | 0.80 | TSHR (0.65) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL4536166 | 0.79 | TSHR (0.59) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL17299694 | 0.78 | TSHR (0.62) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL18885323 | 0.78 | TSHR (0.62) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL5266458 | 0.78 | TSHR (0.70) | TSHRPPARACYP2C9CYP2C8TDP1 | |
| SCHEMBL15085817 | 0.77 | TSHR (0.60) | TSHRPPARACYP2C9CYP2C8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |