Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.36 |
| ▸ | RAMP1 | O60894 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020147 | 0.87 | CALCRL (0.34) | CALCRLRAMP1 | |
| SCHEMBL10119955 | 0.81 | TDP2 (0.39) | — | |
| SCHEMBL5020104 | 0.73 | CALCRL (0.74) | CALCRLRAMP1 | |
| SCHEMBL29559656 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| SCHEMBL31084957 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| SCHEMBL14933346 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| SCHEMBL29518081 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| SCHEMBL3694253 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| SCHEMBL29997203 | 0.72 | CALCRL (0.61) | CALCRLRAMP1 | |
| Hydrochloric Acid SCHEMBL31126002 | 0.71 | CALCRL (0.60) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064910-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-05-18 | — | — | WO | disclosed |