Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 16/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020086 | 0.87 | CALCRL (0.36) | CALCRLRAMP1 | |
| SCHEMBL31084968 | 0.74 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL20664259 | 0.74 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL31126005 | 0.74 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL29517994 | 0.74 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL4571727 | 0.74 | CALCRL (0.58) | CALCRLRAMP1 | |
| SCHEMBL12696572 | 0.73 | CRBN (0.39) | CALCRLCRBNDDB1 | |
| SCHEMBL31126018 | 0.72 | CALCRL (0.42) | CALCRLRAMP1 | |
| SCHEMBL28721100 | 0.72 | CALCRL (0.42) | CALCRLRAMP1 | |
| SCHEMBL22796344 | 0.72 | CALCRL (0.42) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064910-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-05-18 | — | — | WO | disclosed |