Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813753 | 0.87 | HDAC1 (0.64) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10581074 | 0.83 | HDAC1 (0.58) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5020673 | 0.82 | HDAC1 (0.70) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL16921280 | 0.81 | ALDH1A1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10995947 | 0.81 | HDAC1 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10587732 | 0.79 | HDAC1 (0.54) | HDAC1HDAC8HSD11B1ALDH1A1HPGD | |
| SCHEMBL1232793 | 0.78 | HDAC1 (0.57) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL11162511 | 0.78 | THRB (0.53) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL11727133 | 0.78 | HDAC1 (0.61) | HDAC1HDAC8HSD11B1HPGDHSD17B10 | |
| Acetic Acid SCHEMBL362668 | 0.77 | ALDH1A1 (0.55) | HDAC1HDAC8HSD11B1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |