Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781458 | 1.00 | CXCR1 (0.39) | CXCR1CXCR2FAAHPTGS1PTGS2 | |
| SCHEMBL5021270 | 0.81 | IDO1 (0.50) | CYP2C9TSHRALDH1A1 | |
| SCHEMBL1784162 | 0.81 | IDO1 (0.50) | CYP2C9TSHRALDH1A1 | |
| SCHEMBL1784538 | 0.78 | TP53 (0.37) | LMNACYP2C9TSHRALDH1A1 | |
| SCHEMBL1781780 | 0.78 | AGXT (0.45) | TSHRALDH1A1 | |
| SCHEMBL5021265 | 0.78 | AGXT (0.45) | TSHRALDH1A1 | |
| SCHEMBL5021267 | 0.78 | TP53 (0.37) | LMNACYP2C9TSHRALDH1A1 | |
| SCHEMBL5021266 | 0.77 | TSHR (0.41) | LMNACYP2C9ESR1TSHRALDH1A1 | |
| SCHEMBL1780734 | 0.77 | TSHR (0.41) | LMNACYP2C9ESR1TSHRALDH1A1 | |
| SCHEMBL5032523 | 0.76 | IDO1 (0.45) | ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168834-B2 | 4-alkyl 1-(3-methoxy-2-propen-1-yl) benzene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168834-B2 | 4-alkyl 1-(3-methoxy-2-propen-1-yl) benzene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | CXCR1 2632/4885CXCR2 3089/4885FAAH 24/4885 |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | CXCR1 2632/4885CXCR2 3089/4885FAAH 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.