Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021266 | 1.00 | TSHR (0.41) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL5021270 | 0.84 | IDO1 (0.50) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL1784162 | 0.84 | IDO1 (0.50) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL5021267 | 0.77 | TP53 (0.37) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL1784538 | 0.77 | TP53 (0.37) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL1781458 | 0.77 | CXCR1 (0.39) | TSHRALDH1A1CYP2C9LMNAESR1 | |
| SCHEMBL5021271 | 0.77 | CXCR1 (0.39) | TSHRALDH1A1CYP2C9LMNAESR1 | |
| SCHEMBL9806304 | 0.74 | ALDH1A1 (0.47) | TSHRNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL1781453 | 0.74 | THRB (0.40) | TSHRNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL1610162 | 0.74 | CYP2C9 (0.42) | TSHRNPC1RAB9AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168834-B2 | 4-alkyl 1-(3-methoxy-2-propen-1-yl) benzene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2012-05-01 | — | — | US | claimed |
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | claimed |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | claimed |
| US-8168834-B2 | 4-alkyl 1-(3-methoxy-2-propen-1-yl) benzene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | TSHR 4820/4885NPC1 1506/4885RAB9A 4804/4885 |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | TSHR 4820/4885NPC1 1506/4885RAB9A 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.