Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAX | Q07812 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSPO | P30536 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607343 | 0.87 | BAX (0.61) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL5024545 | 0.73 | MAPT (0.45) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL5026836 | 0.72 | KRAS (0.46) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL20704845 | 0.68 | BAX (0.61) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL608294 | 0.68 | BAX (0.88) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL607333 | 0.68 | BAX (0.88) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL607334 | 0.68 | BAX (0.88) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL609012 | 0.68 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL29716701 | 0.68 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL609455 | 0.68 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |