Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270775 | 0.73 | HPGD (0.42) | GRM7SMN1; SMN2TSHRLMNAHPGD | |
| SCHEMBL25762234 | 0.73 | HPGD (0.42) | GRM7SMN1; SMN2TSHRLMNAHPGD | |
| SCHEMBL5914697 | 0.71 | MAOB (0.38) | TSHRHPGD | |
| SCHEMBL30146748 | 0.70 | MAOA (0.39) | TSHRHPGD | |
| SCHEMBL7557445 | 0.70 | MAOA (0.39) | TSHRHPGD | |
| SCHEMBL29615809 | 0.69 | NFKB1 (0.39) | CYP3A4HSP90AB1MAPT | |
| SCHEMBL3283381 | 0.69 | NFKB1 (0.39) | CYP3A4HSP90AB1MAPT | |
| SCHEMBL5022990 | 0.69 | HTT (0.43) | SMN1; SMN2TSHRHPGDMEN1KMT2A | |
| SCHEMBL10137660 | 0.68 | GRM7 (0.47) | GRM7GAAMAPT | |
| SCHEMBL14900911 | 0.68 | GRM7 (0.47) | GRM7GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931995-A2 | METHODS FOR THE DIAGNOSIS OF COLORECTAL CANCER AND OVARIAN CANCER HEALTH STATES | Phenomenome Discoveries Inc. (CA) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007030928-A2 | METHOD FOR THE DIAGNOSIS OF COLORECTAL CANCER AND OVARIAN CANCER BY THE MEASUREMENT OF VITAMIN E-RELATED METABOLITES | PHENOMENOME DISCOVERIES INC. (CA) | 2007-03-22 | — | — | WO | disclosed |