Ethyl Fumarate

Ethyl Fumarate

SCHEMBL502319

CCOC(=O)/C=C\C(=O)O.COC

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.91
MAPT P10636 5/20 0.46
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
LMNA P02545 2/20 0.41
MDM2 Q00987 2/20 0.41
MDM4 O15151 1/20 0.41
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Fumarate SCHEMBL60568 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL9193839 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL10994275 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Ethyl Fumarate SCHEMBL17667143 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Ethyl Fumarate SCHEMBL1133858 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Ethyl Fumarate SCHEMBL1133862 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL10994278 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL19873394 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Ethyl Fumarate SCHEMBL60569 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12
Ethyl Fumarate SCHEMBL30986728 0.95 HCAR2 (1.00) HCAR2MAPTATMNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160193785-A1 3D PRINTER FOR PRINTING A PLURALITY OF MATERIAL TYPES Voxel8, Inc. 2016-07-07 US disclosed
US-8187500-B2 Biphasic inks THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-05-29 US disclosed
US-20120128805-A1 LONG-LASTING GUSTATORY AND/OR OLFACTORY AVERSION VETERINARY COMPOSITIONS FOR BEHAVIOR MODIFICATION VET PLANET, LLC (US) 2012-05-24 US disclosed
US-8104433-B2 Long-lasting gustatory and/or olfactory aversion veterinary compositions for behavior modification VET PLANET, LLC (US) 2012-01-31 US disclosed
US-7922939-B2 Metal nanoparticle inks THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2011-04-12 US disclosed
US-20100096596-A1 BIPHASIC INKS NATIONAL SCIENCE FOUNDATION 2010-04-22 US disclosed
WO-2010040034-A2 METAL NANOPARTICLE INKS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-04-08 WO disclosed
US-20100084599-A1 METAL NANOPARTICLE INKS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-04-08 US disclosed
US-20100016462-A1 Long-Lasting Gustatory and/or Olfactory Aversion Veterinary Compositions for Behavior Modification VET PLANET, LLC 2010-01-21 US disclosed
EP-1777255-A2 Image making medium Hyman, Sydney (US) 2007-04-25 EP disclosed
US-7053125-B2 Controlled dispersion of colloidal suspension by comb polymers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2006-05-30 US disclosed
US-20040096469-A1 Controlled dispersion of colloidal suspensions by comb polymers VERIFI LLC 2004-05-20 US disclosed
US-20030008078-A1 Oil-and water-repellent finishes for textiles NANO-TEX, LLC 2003-01-09 US disclosed
US-6472476-B1 PREPARATION FOR FIBROUS AND OTHER SUBSTRATES, THE PREPARATION COMPRISING A FLUORINATED POLYMER AND A TACKING MONOMER, OLIGOMER OR POLYMER CONTAINING AT LEAST ONE ANHYDRIDE FUNCTIONAL GROUP OR A GROUP CAPABLE OF FORMING AN ANHYDRIDE NANO-TEX, LLC 2002-10-29 US disclosed