SCHEMBL5023637

SCHEMBL5023637

[N-]=[N+]=C(c1ccccc1)P(=O)(O)OC(=O)[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.30
ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19063571 0.76 ANPEP (0.40) LAP3ANPEP
SCHEMBL6257649 0.76
SCHEMBL5023615 0.76
SCHEMBL28731460 0.74 KMT2A (0.39) ANPEP
SCHEMBL7782151 0.73 SLC1A3 (0.37) LAP3ANPEP
SCHEMBL7782152 0.73 SLC1A3 (0.37) LAP3ANPEP
Histidine SCHEMBL17316320 0.72 SLC7A5 (0.44)
SCHEMBL713212 0.72 LTA4H (0.44) LAP3
SCHEMBL3155213 0.72 ALPI (0.46) LAP3ANPEP
SCHEMBL729057 0.72 LTA4H (0.44) LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1616966-B1 Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates and enzyme inhibition assays SIEMENS HEALTHCARE DIAGNOSTICS (US) 2008-11-26 EP disclosed
EP-1616966-A2 Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates and enzyme inhibition assays Bayer Corporation (US) 2006-01-18 EP disclosed
US-20050186606-A1 Methods and compositions for detecting nucleic acids APPLIED BIOSYSTEMS, LLC 2005-08-25 US disclosed
WO-2005077125-A2 METHODS AND COMPOSITIONS FOR DETECTING NUCLEIC ACIDS APPLERA CORPORATION (US) 2005-08-25 WO disclosed
EP-0832296-B1 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS BAYER AG (US) 2005-08-24 EP disclosed
US-5853974-A Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates CHIRON CORPORATION (US) 1998-12-29 US disclosed
US-5780227-A LABELLED OLIGONUCLEOTIDE TO GENERATE A TARGET-DEPENDENT SIGNALING NUCLEIC ACID HYBRIDIZATION TEST BY MINIMIZING BACKGROUND NOISE BY BEING A HOMOGENEOUS POPULATION OF PROBES; GENOTYPING; ANTISENSE AND APTAMER THERAPY; MUTANT ANALYSIS SIEMENS HEALTHCARE DIAGNOSTICS INC. 1998-07-14 US disclosed
EP-0832296-A2 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS CHIRON CORPORATION (US) 1998-04-01 EP disclosed
WO-1996041015-A9 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS 1997-02-20 WO disclosed
WO-1996041015-A2 ENHANCEMENT OF ALKALINE PHOSPHATASE WITH SDS IN CHEMILUMINESCENT SUBSTRATES AND ENZYME INHIBITION ASSAYS CHIRON CORPORATION (US) 1996-12-19 WO disclosed