Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713212 | 1.00 | LTA4H (0.44) | LTA4HLAP3IDO1SLC15A1TACR1 | |
| Hydrochloric Acid SCHEMBL9515675 | 0.99 | LTA4H (0.43) | LTA4HLAP3IDO1SLC15A1TACR1 | |
| Hydrochloric Acid SCHEMBL7273689 | 0.99 | LTA4H (0.43) | LTA4HLAP3IDO1SLC15A1TACR1 | |
| Hydrochloric Acid SCHEMBL7273682 | 0.99 | LTA4H (0.43) | LTA4HLAP3IDO1SLC15A1TACR1 | |
| Hydrochloric Acid SCHEMBL9515682 | 0.99 | LTA4H (0.43) | LTA4HLAP3IDO1SLC15A1TACR1 | |
| SCHEMBL29854006 | 0.89 | LTA4H (0.39) | LTA4HLAP3IDO1SLC15A1SLC1A3 | |
| SCHEMBL3626015 | 0.87 | NPC1 (0.40) | LTA4HALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL3155213 | 0.87 | ALPI (0.46) | LTA4HLAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL7353357 | 0.86 | LMNA (0.43) | LTA4HLAP3IDO1TACR1ALDH1A1 | |
| SCHEMBL7280864 | 0.86 | LMNA (0.43) | LTA4HLAP3IDO1TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556438-B | Multi-responsive cross-linked polymer, drug-loaded nano micelle and preparation method thereof | 西南民族大学 | 2020-05-12 | — | — | CN | claimed |
| US-9598288-B2 | Method for preparing zinc-histidine self-assembly biomimetric complex, zinc-histidine self-assembly complex prepared by said method, and method for reducing carbon dioxide using said zinc-histidine self-assembly complex | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2017-03-21 | — | — | US | claimed |
| US-20150151974-A1 | METHOD FOR PREPARING ZINC-HISTIDINE SELF-ASSEMBLY BIOMIMETRIC COMPLEX, ZINC-HISTIDINE SELF-ASSEMBLY COMPLEX PREPARED BY SAID METHOD, AND METHOD FOR REDUCING CARBON DIOXIDE USING SAID ZINC-HISTIDINE SELF-ASSEMBLY COMPLEX | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-04 | — | — | US | claimed |
| CN-102241674-B | Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester | UNIV CAPITAL MEDICAL | 2012-09-12 | — | — | CN | claimed |
| CN-101906102-B | Beta-carboline alkaloid derivative, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-08-29 | — | — | CN | claimed |
| CN-102250202-A | 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof | UNIV CAPITAL MEDICAL | 2011-11-23 | — | — | CN | claimed |
| CN-102241674-A | Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester | UNIV CAPITAL MEDICAL | 2011-11-16 | — | — | CN | claimed |
| CN-101497615-B | Substituted purine, preparation and use in medicine | ZHEJIANG MED XINCHANG PHARM | 2010-12-15 | — | — | CN | claimed |
| CN-101906102-A | Beta-carboline alkaloid derivative, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2010-12-08 | — | — | CN | claimed |
| CN-101497615-A | Substituted purine, preparation and use in medicine | XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) | 2009-08-05 | — | — | CN | claimed |
| EP-0565646-A4 | — | — | 1994-08-03 | — | — | EP | claimed |
| EP-0565646-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1992018518-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1992-10-29 | — | — | WO | claimed |
| JP-1026596-A | — | — | None | — | — | JP | disclosed |
| CN-107556438-B | Multi-responsive cross-linked polymer, drug-loaded nano micelle and preparation method thereof | 西南民族大学 | 2020-05-12 | — | — | CN | disclosed |
| US-9598288-B2 | Method for preparing zinc-histidine self-assembly biomimetric complex, zinc-histidine self-assembly complex prepared by said method, and method for reducing carbon dioxide using said zinc-histidine self-assembly complex | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2017-03-21 | — | — | US | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4665056-A | CENTRAL NERVOUS SYSTEM DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0168042-A2 | Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |