⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114702 | 0.80 | — | — | |
| SCHEMBL5017147 | 0.79 | — | — | |
| SCHEMBL30285882 | 0.77 | — | — | |
| SCHEMBL27872648 | 0.77 | — | — | |
| SCHEMBL11687259 | 0.76 | — | — | |
| SCHEMBL5017358 | 0.75 | — | — | |
| SCHEMBL4541174 | 0.73 | — | — | |
| SCHEMBL28614394 | 0.68 | MAPT (0.34) | — | |
| Hydrochloric Acid SCHEMBL4324251 | 0.68 | — | — | |
| SCHEMBL29145824 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488778-B1 | A radioactive iodine compound for labeling an antibody | SHIONOGI & CO (JP) | 1994-11-09 | — | — | EP | claimed |
| EP-1945606-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052938-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-05-10 | — | — | WO | disclosed |
| JP-2000129257-A | VEGETABLE ANTIOXIDANT AND REMEDY AGAINST GASTRIC ULCER OR THE LIKE | NIPPON BEET SUGAR MFG CO LTD | 2000-05-09 | — | — | JP | disclosed |
| EP-0488778-B1 | A radioactive iodine compound for labeling an antibody | SHIONOGI & CO (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5252748-A | Highly sensitive measurement | SHIONOGI & CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0488778-A2 | A radioactive iodine compound for labeling an antibody | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |