⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023745 | 0.79 | — | — | |
| SCHEMBL8102865 | 0.79 | — | — | |
| SCHEMBL2220182 | 0.79 | — | — | |
| SCHEMBL11687259 | 0.76 | — | — | |
| SCHEMBL334646 | 0.74 | — | — | |
| SCHEMBL16286346 | 0.72 | — | — | |
| SCHEMBL28609118 | 0.68 | — | — | |
| SCHEMBL1331497 | 0.67 | LTA4H (0.30) | — | |
| SCHEMBL18856410 | 0.66 | — | — | |
| SCHEMBL20876924 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945606-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052938-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-05-10 | — | — | WO | disclosed |