SCHEMBL50238

SCHEMBL50238

O=C(c1ccccc1)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.74
ALDH1A1 P00352 7/20 0.74
NPC1 O15118 6/20 0.74
HPGD P15428 5/20 0.74
RAB9A P51151 5/20 0.74
MAPT P10636 5/20 0.74
TSHR P16473 3/20 0.74
TP53 P04637 3/20 0.74
HSD17B10 Q99714 2/20 0.74
ALOX15 P16050 2/20 0.74
L3MBTL1 Q9Y468 2/20 0.74
LMNA P02545 2/20 0.74
STAT1 P42224 1/20 0.74
PRKDC P78527 2/20 0.68
PIK3CD O00329 1/20 0.68
PIK3CA P42336 1/20 0.68
PIK3CB P42338 1/20 0.68
PIK3CG P48736 1/20 0.68
USP2 O75604 1/20 0.68
MAPK1 P28482 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14982101 0.94 NPC1 (0.76) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL2742813 0.93 NPC1 (0.66) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL12757110 0.91 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL12757135 0.91 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL14982132 0.89 ALDH1A1 (0.61) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL14982102 0.88 KMO (0.65) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
Ether SCHEMBL27901382 0.88 ALDH1A1 (0.59) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL12757173 0.88 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL14982100 0.88 MEN1 (0.58) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A
SCHEMBL8522837 0.87 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1NPC1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-111522200-B Negative PSPI resin for 12-inch silicon wafer and preparation method and application thereof 中国科学院化学研究所 2021-07-27 CN claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
CN-113135835-A Method for exciting C-C bond breaking acylation and application 广州中医药大学(广州中医药研究院) 2021-07-20 CN claimed
CN-111522200-A Negative PSPI resin for 12-inch silicon wafer and preparation method and application thereof 中国科学院化学研究所 2020-08-11 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
US-8941006-B2 Apparatus and method for extending polyolefin containing photovoltaic panel life span FINA TECHNOLOGY, INC. (US) 2015-01-27 US claimed
EP-1932195-B1 SCAVENGER MATERIALS IN FUEL CARTRIDGE BIC SOC (FR) 2013-05-01 EP claimed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP claimed
WO-1999039247-A1 PHOTOPOLYMERIZATION COMPOSITIONS INCLUDING MALEIMIDES AND PROCESSES FOR USING THE SAME FIRST CHEMICAL CORPORATION (US) 1999-08-05 WO claimed
US-5648020-A PACKAGING W. R. GRACE & CO.-CONN. (US) 1997-07-15 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0184233-B1 DRUG DISPENSING WOUND DRESSING THERMEDICS, INC. (US) 1990-05-23 EP claimed
EP-0137228-B1 PHOTOPOLYMERIZABLE COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed