Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.47 |
| ▸ | ITGAV | P06756 | 11/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028147 | 0.75 | ITGB3 (0.79) | ITGB3ITGAV | |
| SCHEMBL5025637 | 0.75 | ITGB3 (0.43) | ITGB3ITGAVHSD17B10KDM4EGAA | |
| SCHEMBL6439441 | 0.74 | ITGB3 (0.51) | ITGB3ITGAVDDX3XMEN1KMT2A | |
| SCHEMBL5025438 | 0.74 | ITGB3 (0.53) | ITGB3ITGAVALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5024074 | 0.73 | ITGB3 (0.48) | ITGB3ITGAVHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL6439442 | 0.73 | ITGB3 (0.50) | ITGB3ITGAVMEN1KMT2APLK4 | |
| SCHEMBL3771108 | 0.69 | ALDH1A1 (0.61) | ITGB3ITGAVAKR1C3DDX3XHSD17B10 | |
| SCHEMBL5028375 | 0.68 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL5026276 | 0.65 | ITGB3 (0.68) | ITGB3ITGAVMAPK1 | |
| SCHEMBL5026328 | 0.65 | ITGB3 (0.70) | ITGB3ITGAVMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | ITGB3 1/4885ITGAV 2/4885AKR1C3 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.