SCHEMBL5024466

SCHEMBL5024466

C=C(C)C(=O)OC(O)C[SiH2]O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014893 0.83 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL16592838 0.74 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL8966139 0.74 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL2443264 0.74 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL25040 0.72 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL10439986 0.72 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL3503946 0.72 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL549696 0.72 TSHR (0.43) TSHRALDH1A1THRB
Methane SCHEMBL7698380 0.71 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL28381594 0.71 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed