Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20953859 | 0.87 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL5014893 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL142824 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1THRB | |
| SCHEMBL5024466 | 0.74 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL23406517 | 0.74 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL8965806 | 0.74 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL15161769 | 0.73 | THRB (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL28993876 | 0.73 | ALDH1A1 (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL7591794 | 0.71 | TSHR (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL272305 | 0.71 | ALDH1A1 (0.41) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9574109-B2 | Surface-modified hydrogels and hydrogel microparticles | DOW CORNING CORPORATION (US) | 2017-02-21 | — | — | US | claimed |
| EP-2536786-A1 | SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | Dow Corning Corporation (US) | 2012-12-26 | — | — | EP | claimed |
| US-20120309623-A1 | SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | DOW SILICONES CORPORATION | 2012-12-06 | — | — | US | claimed |
| WO-2011109174-A1 | SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | DOW CORNING CORPORATION (US) | 2011-09-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309623-A1 | SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | CD44, EPCAM, ITGAM | TSHR 1190/4885ALDH1A1 204/4885THRB 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.