Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.54 |
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022259 | 0.81 | CTSK (0.48) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL5018049 | 0.79 | CTSK (0.43) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL5017262 | 0.77 | CTSK (0.39) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL5017270 | 0.76 | CTSK (0.42) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL5024453 | 0.75 | CTSK (0.56) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL13709388 | 0.74 | CTSK (0.57) | CTSKKCNH2CTSSCTSBNOS3 | |
| SCHEMBL5017183 | 0.73 | CTSK (0.55) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL8269456 | 0.71 | CTSK (1.00) | CTSKKCNH2CTSSCTSBHRH3 | |
| SCHEMBL4446030 | 0.70 | CTSK (1.00) | CTSKKCNH2CTSSCTSB | |
| SCHEMBL4440710 | 0.70 | CTSK (1.00) | CTSKKCNH2CTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758870-B1 | 4-PHENYL-PYRIMIDINE-2-CARBONITRILE DERIVATIVES | ORGANON NV (NL) | 2008-08-13 | — | — | EP | claimed |