Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024559 | 0.91 | HTR1A (0.45) | MEN1ALDH1A1KMT2APIN1 | |
| SCHEMBL5022928 | 0.91 | HTR1A (0.45) | MEN1ALDH1A1KMT2APIN1 | |
| SCHEMBL5024376 | 0.89 | HTR1A (0.46) | MEN1ALDH1A1KMT2APIN1 | |
| SCHEMBL5024379 | 0.89 | HTR1A (0.46) | MEN1ALDH1A1KMT2APIN1 | |
| Hydrochloric Acid SCHEMBL6711694 | 0.88 | PIN1 (0.50) | PIN1 | |
| Hydrochloric Acid SCHEMBL5025325 | 0.88 | HTR1A (0.46) | MEN1ALDH1A1KMT2APIN1 | |
| Hydrochloric Acid SCHEMBL5025321 | 0.88 | HTR1A (0.46) | MEN1ALDH1A1KMT2APIN1 | |
| SCHEMBL5024505 | 0.86 | HTR1A (0.49) | — | |
| SCHEMBL5024506 | 0.86 | HTR1A (0.49) | — | |
| SCHEMBL5024483 | 0.84 | MCHR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474145-B1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | EP | claimed |