SCHEMBL5024591

SCHEMBL5024591

C=CC(=O)OCC[SiH]1CCCCO1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
HPGD P15428 1/20 0.39
THRB P10828 2/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9325846 0.91 TSHR (0.51) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL5016059 0.91 TSHR (0.51) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL10915054 0.85 TSHR (0.41) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL10425424 0.77
SCHEMBL10695959 0.76 TSHR (0.32) TSHR
SCHEMBL4876333 0.73
Acrylamide SCHEMBL29002374 0.72 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL29065819 0.71 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL246363 0.70
Acrylic Acid SCHEMBL27709464 0.69 LMNA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115277-B2 Porous polyolefin resin film MITSUBISHI PLASTICS, INC. (JP) 2015-08-25 US disclosed
US-20130236793-A1 POROUS POLYOLEFIN RESIN FILM MITSUBISHI PLASTICS, INC. (JP) 2013-09-12 US disclosed
EP-2626380-A1 POROUS POLYOLEFIN RESIN FILM Mitsubishi Plastics, Inc. (JP) 2013-08-14 EP disclosed
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed