SCHEMBL5024731

SCHEMBL5024731

CC(O)COP(=O)(O)ON

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 3/20 0.35
PGD P52209 2/20 0.34
P2RY10 O00398 4/20 0.33
GPR174 Q9BXC1 3/20 0.33
GPR34 Q9UPC5 2/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.32
MPI P34949 1/20 0.31
ANPEP P15144 3/20 0.31
ERAP1 Q9NZ08 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7159089 0.89 MAPK1 (0.40) LAP3PGDP2RY10GPR174GPR34
SCHEMBL28584705 0.84 ANPEP (0.37) LAP3PGDANPEPERAP1
SCHEMBL23387514 0.78 PGK1 (0.33) LAP3PGDP2RY10GPR174GPR34
SCHEMBL27845283 0.77 SMN1; SMN2 (0.41) PGDP2RY10GPR174GPR34PGK1
SCHEMBL10760222 0.77 HSD17B10 (0.50) P2RY10GPR174GPR34HSD17B10
SCHEMBL3340733 0.77
SCHEMBL1079057 0.77
SCHEMBL3344507 0.77
SCHEMBL7157943 0.74 TSHR (0.41) LAP3PGDPGK1PGK2MAPK1
SCHEMBL269622 0.74 CYP3A4 (0.38) LAP3PGK1PGK2ANPEPERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7329515-B2 Solid support for the synthesis of 3′-amino oligonucleotides SIGMA-ALDRICH CO. (US) 2008-02-12 US disclosed
US-20040220397-A1 Solid support for the synthesis of 3'-amino oligonucleotides PROLIGO LLC (US) 2004-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220397-A1 Solid support for the synthesis of 3'-amino oligonucleotides PCNA, DERA, RNGTT LAP3 1061/4885PGD 1546/4885P2RY10 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.