Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134140 | 0.89 | CYP2C19 (0.73) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL11134146 | 0.85 | CYP3A4 (0.56) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL5032132 | 0.84 | ALDH1A1 (0.52) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL8851966 | 0.82 | CYP2C19 (0.67) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| Acrylic Acid SCHEMBL9576773 | 0.80 | CYP2C9 (0.54) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL2164224 | 0.80 | CYP2C19 (0.79) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| Acrylic Acid SCHEMBL8878215 | 0.79 | CYP3A4 (0.49) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| Acrylic Acid SCHEMBL9820576 | 0.79 | CYP3A4 (0.49) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL6397556 | 0.78 | CYP2C19 (0.61) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL4594355 | 0.78 | CYP2C19 (0.66) | CYP2C19CYP3A4CYP2C9TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7267914-B2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2007-09-11 | — | — | US | claimed |
| US-7348115-B2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2008-03-25 | — | — | US | disclosed |
| US-7267914-B2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2007-09-11 | — | — | US | disclosed |
| US-20050170271-A1 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | YAMANAMI HIROFUMI (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20030232265-A1 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1324139-A2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | Ricoh Company, Ltd. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5670284-A | HAVING CHARGE GENERATING LAYER COMPRISING POLYALKYLENE GLYCOL AND/OR ESTER OR ETHER THEREOF AND/OR CROWN ETHER, CHARGE TRANSPORT LAYER COMPRISING ANTIOXIDANT | RICOH COMPANY, LTD. (JP) | 1997-09-23 | — | — | US | disclosed |