SCHEMBL502598

SCHEMBL502598

O=C(O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.71
PLA2G10 O15496 1/20 0.69
PLA2G2A P14555 1/20 0.69
LMNA P02545 1/20 0.69
TSHR P16473 4/20 0.66
DAO P14920 1/20 0.59
NAPRT Q6XQN6 1/20 0.59
ALDH1A1 P00352 1/20 0.58
CALM1 P0DP23 1/20 0.57
TP53 P04637 1/20 0.57
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
HSD17B10 Q99714 1/20 0.55
HNF4A P41235 1/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482345 1.00 SRD5A2 (0.71) SRD5A2PLA2G10PLA2G2ALMNATSHR
Ammonia Solution, Strong SCHEMBL28313730 0.98 SRD5A2 (0.69) SRD5A2PLA2G10PLA2G2ALMNATSHR
Benzoic Acid SCHEMBL7064148 0.95 SRD5A2 (0.71) SRD5A2PLA2G10PLA2G2ALMNATSHR
SCHEMBL68390 0.93 SRD5A2 (0.69) SRD5A2PLA2G10PLA2G2ALMNATSHR
Hydrochloric Acid SCHEMBL25188150 0.90 SRD5A2 (0.67) SRD5A2PLA2G10PLA2G2ALMNATSHR
Hydrochloric Acid SCHEMBL7133360 0.90 SRD5A2 (0.67) SRD5A2PLA2G10PLA2G2ALMNATSHR
Diphenylmethane SCHEMBL7835581 0.89 CA12 (0.67) SRD5A2PLA2G10PLA2G2ALMNATSHR
SCHEMBL1247035 0.86 PLA2G10 (0.69) SRD5A2PLA2G10PLA2G2ALMNATSHR
SCHEMBL11673315 0.86 SRD5A2 (0.62) SRD5A2PLA2G10PLA2G2ALMNATSHR
SCHEMBL1926270 0.86 HDAC1 (0.64) SRD5A2TSHRDAONAPRTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 972 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117180247-A Application of 2-amino-6-methylphenol derivative as iron death inhibitor in preparation of medicines for preventing and treating osteoarthritis 山东第一医科大学第一附属医院(山东省千佛山医院) 2023-12-08 CN claimed
US-RE46965-E1 Intermediates for the preparation of analogs of Halichondrin B EISAI R&D MANAGEMENT CO., LTD. (JP) 2018-07-24 US claimed
EP-1797186-B1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NAT RES COUNCIL CANADA (CA) 2016-05-25 EP claimed
US-RE45324-E1 Intermediates for the preparation of analogs of halichondrin B EISAI R&D MANAGEMENT CO., LTD. (JP) 2015-01-06 US claimed
US-8728759-B2 Reverse cumate repressor mutant NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2014-05-20 US claimed
US-8252556-B2 Reverse cumate repressor mutant NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-08-28 US claimed
CN-102448978-A Novel Glucocorticoid Receptor Agonists PFIZER LTD 2012-05-09 CN claimed
US-7982060-B2 Intermediates for the preparation of analogs of Halichondrin B EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-07-19 US claimed
US-20110171686-A1 REVERSE CUMATE REPRESSOR MUTANT NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-07-14 US claimed
US-20090176275-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-07-09 US claimed
WO-2006037215-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2006-04-13 WO claimed
EP-1563306-A1 PHOTOLINKER MACROMOLECULES, METALLIC SUBSTRATES AND LIGANDS MODIFIED WITH SAID LINKERS, AND PROCESS OF PREPARATION THEREOF C.S.E.M. CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA (CH) 2005-08-17 EP claimed
WO-2005052580-A1 PHOTOLINKER MACROMOLECULES, METALLIC SUBSTRATES AND LIGANDS MODIFIED WITH SAID LINKERS, AND PROCESS OF PREPARATION THEREOF C.S.E.M. CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE (CH) 2005-06-09 WO claimed
US-20040205834-A1 System for inducible expression in eukaryotic cells NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-10-14 US claimed
EP-1385946-A2 A SYSTEM FOR INDUCIBLE EXPRESSION IN EUKARYOTIC CELLS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-02-04 EP claimed
WO-2002088346-A2 A SYSTEM FOR INDUCIBLE EXPRESSION IN EUKARYOTIC CELLS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2002-11-07 WO claimed
EP-0451261-B1 AGENT AND PROCESS FOR BLEACHING HAIR UNDER THE ACTION OF LIGHT Wella Aktiengesellschaft (DE) 1993-09-15 EP claimed
EP-0451261-A1 AGENT AND PROCESS FOR BLEACHING HAIR UNDER THE ACTION OF LIGHT. WELLA AG (DE) 1991-10-16 EP claimed
WO-1991006279-A2 AGENT AND PROCESS FOR BLEACHING HAIR UNDER THE ACTION OF LIGHT WELLA AKTIENGESELLSCHAFT (DE) 1991-05-16 WO claimed
US-4880850-A POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1989-11-14 US claimed