Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.71 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HNF4A | P41235 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502598 | 1.00 | SRD5A2 (0.71) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| Ammonia Solution, Strong SCHEMBL28313730 | 0.98 | SRD5A2 (0.69) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| Benzoic Acid SCHEMBL7064148 | 0.95 | SRD5A2 (0.71) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| SCHEMBL68390 | 0.93 | SRD5A2 (0.69) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| Hydrochloric Acid SCHEMBL25188150 | 0.90 | SRD5A2 (0.67) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| Hydrochloric Acid SCHEMBL7133360 | 0.90 | SRD5A2 (0.67) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| Diphenylmethane SCHEMBL7835581 | 0.89 | CA12 (0.67) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| SCHEMBL1247035 | 0.86 | PLA2G10 (0.69) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| SCHEMBL11673315 | 0.86 | SRD5A2 (0.62) | SRD5A2PLA2G10PLA2G2ALMNATSHR | |
| SCHEMBL1926270 | 0.86 | HDAC1 (0.64) | SRD5A2TSHRDAONAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763509-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006002474-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2006-01-12 | — | — | WO | disclosed |